SCHEMBL21775397

SCHEMBL21775397

CC(C)(C)N(C(=O)O)S(=O)(=O)N1CC(CC#N)(N2CCC(=O)CC2)C1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 14/20 0.40
JAK2 O60674 6/20 0.33
JAK1 P23458 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21775411 0.76 KDM1A (0.41) KDM1AJAK2JAK1
SCHEMBL21775398 0.75 KDM1A (0.37) KDM1AJAK2JAK1
SCHEMBL16989462 0.66 KDM1A (0.41) KDM1AJAK2JAK1
SCHEMBL18820434 0.64 KDM1A (0.42) KDM1AJAK1
Hydrochloric Acid SCHEMBL21775423 0.63 KDM1A (0.41) KDM1AJAK1
SCHEMBL26927404 0.61 HSD11B1 (0.35)
SCHEMBL21788635 0.61 KDM1A (0.42) KDM1AJAK2JAK1
SCHEMBL21784420 0.60 KDM1A (0.41) KDM1A
SCHEMBL16989418 0.59 KDM1A (0.55) KDM1AJAK2JAK1
SCHEMBL17009075 0.59 MMP2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10968200-B2 Salts of an LSD1 inhibitor and processes for preparing the same INCYTE CORPORATION (US) 2021-04-06 US disclosed
US-20200071289-A1 SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME WILMINGTON PHARMATECH 2020-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200071289-A1 SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME KDM1A, KDM1B, KDM2A KDM1A 1/4885JAK2 441/4885JAK1 864/4885
US-10968200-B2 Salts of an LSD1 inhibitor and processes for preparing the same KDM1A, KDM1B, KDM2A KDM1A 1/4885JAK2 441/4885JAK1 864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.