SCHEMBL21775463

SCHEMBL21775463

O=C(O)/C=C(/C=C/C(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.53
TP53 P04637 1/20 0.53
EGLN1 Q9GZT9 1/20 0.53
EGLN3 Q9H6Z9 1/20 0.53
HCAR2 Q8TDS4 8/20 0.37
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
GAA P10253 1/20 0.32
ALOX15 P16050 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GABRR1 P24046 2/20 0.32
GABRR2 P28476 2/20 0.32
BLM P54132 2/20 0.32
GABRR3 A8MPY1 1/20 0.32
LMNA P02545 1/20 0.32
APEX1 P27695 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346500 1.00 TSHR (0.53) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL2721423 1.00 TSHR (0.53) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL346501 1.00 TSHR (0.53) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL28157428 0.78 TSHR (0.33) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL9311666 0.77 TSHR (0.53) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL2351110 0.73 TSHR (0.82) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL344295 0.73 TSHR (0.82) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL344296 0.73 TSHR (0.82) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL16234752 0.73 TSHR (0.82) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL3777151 0.73 TSHR (0.82) TSHRTP53EGLN1EGLN3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081068-A Lignin degrading microorganism and separation method and application thereof 2026-05-26 CN disclosed
US-20250336533-A1 Methods and Systems for Evaluation of Lupus Based on Ancestry-Associated Molecular Pathways AMPEL BIOSOLUTIONS LLC (US) 2025-10-30 US disclosed
CN-116096857-B Biosynthesis of commodity chemicals from oil palm empty fruit cluster lignin 新加坡国立大学 2025-09-12 CN disclosed
WO-2023213310-A9 CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF 太阳雨林(北京)生物医药有限公司 2025-02-20 WO disclosed
US-20250037787-A1 CONCENTRATION BOUNDS IN LARGE NETWORKS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-01-30 US disclosed
CN-117776407-A Application of amidase and phenol hydroxylase in degradation of triclocarban and intermediate products thereof 东北农业大学 2024-03-29 CN disclosed
WO-2023213310-A1 CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF 太阳雨林(北京)生物医药有限公司 2023-11-09 WO disclosed
US-11807873-B2 Conversion of S-lignin compounds to useful intermediates ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2023-11-07 US disclosed
CN-116096857-A Biosynthesis of commodity chemicals from oil palm empty fruit cluster lignin 新加坡国立大学 2023-05-09 CN disclosed
CN-116096857-A Biosynthesis of commodity chemicals from oil palm empty fruit cluster lignin 新加坡国立大学 2023-05-09 CN disclosed
CN-115607677-A Compound for preventing, preventing or treating microbial infection and preparation and application thereof 太阳雨林(北京)生物医药有限公司 2023-01-17 CN disclosed
CN-114569726-B Compound for preventing, preventing or treating microbial infection and preparation method and application thereof 太阳雨林(北京)生物医药有限公司 2022-10-28 CN disclosed
CN-114788872-A Compound for preventing, preventing or treating microbial infection and preparation and application thereof 太阳雨林(北京)生物医药有限公司 2022-07-26 CN disclosed
CN-114569726-A Compound for preventing, preventing or treating microbial infection and preparation method and application thereof 太阳雨林(北京)生物医药有限公司 2022-06-03 CN disclosed
US-20220119849-A1 CONVERSION OF S-LIGNIN COMPOUNDS TO USEFUL INTERMEDIATES Alliance for Energy Innovation, LLC 2022-04-21 US disclosed
US-11136601-B2 Conversion of S-lignin compounds to useful intermediates ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2021-10-05 US disclosed
CN-106795486-B Coryneform bacterium transformant and method for producing organic compound using same 公益财团法人地球环境产业技术研究机构 2021-06-08 CN disclosed
US-20200071731-A1 CONVERSION OF S-LIGNIN COMPOUNDS TO USEFUL INTERMEDIATES Alliance for Energy Innovation, LLC 2020-03-05 US disclosed
CN-104603277-A Alternative pathways to adipates and adipic acid by combined fermentation and catalytic methods BIOAMBER SAS 2015-05-06 CN disclosed