Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.41 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.41 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20273893 | 0.80 | DHFR (0.52) | AGXTALKBH1DHFRKMOLMNA | |
| SCHEMBL22466056 | 0.80 | DHFR (0.49) | DRD4DRD2DRD3AGXTALKBH1 | |
| SCHEMBL20273944 | 0.79 | IRAK4 (0.47) | AGXTALKBH1DHFRKMOLMNA | |
| SCHEMBL22725096 | 0.79 | DHFR (0.43) | AGXTALKBH1DHFRKMOLMNA | |
| SCHEMBL4507051 | 0.78 | AGXT (0.65) | DRD4AGXTKMOLMNASMN1; SMN2 | |
| SCHEMBL13661992 | 0.75 | NOTUM (0.46) | DRD4DRD2DRD3HTR2CLMNA | |
| SCHEMBL27329825 | 0.74 | LMNA (0.71) | AGXTDHFRKMOLMNASMN1; SMN2 | |
| SCHEMBL9608917 | 0.73 | DRD4 (0.55) | DRD4DRD2DRD3HTR2CLMNA | |
| SCHEMBL26028861 | 0.72 | EPHX2 (0.47) | DRD4DRD2DRD3LMNASMN1; SMN2 | |
| SCHEMBL14961830 | 0.72 | HTT (0.56) | DRD4DRD2DRD3AGXTDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10988482-B2 | IRAK4 inhibitor and use thereof | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2021-04-27 | — | — | US | disclosed |
| US-20200062775-A1 | IRAK4 INHIBITOR AND USE THEREOF | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10988482-B2 | IRAK4 inhibitor and use thereof | IRAK4, IRAK1, IRAK2 | DRD4 4483/4885DRD2 4827/4885DRD3 4814/4885 |
| US-20200062775-A1 | IRAK4 INHIBITOR AND USE THEREOF | IRAK4, IRAK1, IRAK2 | DRD4 4483/4885DRD2 4827/4885DRD3 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.