Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24668130 | 0.91 | METAP1 (0.41) | METAP1LMNAOPRM1 | |
| SCHEMBL23862861 | 0.87 | OPRM1 (0.48) | METAP1LMNAOPRM1ALDH1A1TDP1 | |
| SCHEMBL5349656 | 0.84 | METAP1 (0.44) | METAP1LMNAOPRM1CYP2D6SPHK1 | |
| Ammonia Solution, Strong SCHEMBL1302715 | 0.83 | OPRM1 (0.44) | LMNAOPRM1CYP2D6SPHK1GMNN | |
| SCHEMBL5371282 | 0.82 | ALDH1A1 (0.44) | LMNAOPRM1ALDH1A1TDP1CYP2D6 | |
| SCHEMBL23072529 | 0.82 | METAP1 (0.35) | METAP1 | |
| SCHEMBL22179713 | 0.82 | TSHR (0.38) | METAP1LMNAOPRM1ALDH1A1TDP1 | |
| SCHEMBL16649023 | 0.80 | OPRM1 (0.52) | LMNAOPRM1ALDH1A1TDP1CYP2D6 | |
| SCHEMBL16111959 | 0.79 | METAP1 (0.41) | METAP1OPRM1ALDH1A1TDP1 | |
| SCHEMBL22609036 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11239114-B2 | Semiconductor device with reduced contact resistance and methods of forming the same | TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) | 2022-02-01 | — | — | US | disclosed |
| US-20210082756-A1 | Semiconductor Device with Reduced Contact Resistance and Methods of Forming the Same | TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) | 2021-03-18 | — | — | US | disclosed |
| US-20200062760-A1 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062760-A1 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | PTPRCAP, PTPRJ, PTPRC | METAP1 1452/4885LMNA 4793/4885OPRM1 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.