Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 15/20 | 0.72 |
| ▸ | STK39 | Q9UEW8 | 5/20 | 0.72 |
| ▸ | PARG | Q86W56 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19868350 | 0.94 | PARG (0.76) | PNLIPSTK39PARGMEN1HSPD1 | |
| SCHEMBL20844338 | 0.91 | PNLIP (0.59) | PNLIPSTK39PARGMEN1HSPD1 | |
| SCHEMBL23685897 | 0.89 | PNLIP (0.80) | PNLIPSTK39PARGMEN1HSPD1 | |
| SCHEMBL22475377 | 0.89 | PNLIP (0.80) | PNLIPSTK39PARGMEN1HSPD1 | |
| SCHEMBL23685774 | 0.84 | PNLIP (0.51) | PNLIPSTK39PARGMEN1HSPD1 | |
| SCHEMBL15164870 | 0.80 | PNLIP (0.77) | PNLIPSTK39PARGMEN1HTT | |
| SCHEMBL29655162 | 0.80 | PNLIP (0.82) | PNLIPSTK39MEN1HSPD1PIK3CA | |
| SCHEMBL24438027 | 0.80 | PNLIP (0.82) | PNLIPSTK39MEN1HSPD1PIK3CA | |
| SCHEMBL23685813 | 0.80 | PNLIP (1.00) | PNLIPSTK39PARGMEN1HSPD1 | |
| Rafoxanide SCHEMBL118031 | 0.80 | PNLIP (1.00) | PNLIPSTK39PARGMEN1HSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3338783-B1 | ANTIBACTERIAL USE OF HALOGENATED SALICYLANILIDES | UNION THERAPEUTICS AS (DK) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022103572-A1 | COMPOUNDS AND METHODS OF INHIBITING BACTERIAL CHAPERONIN SYSTEMS | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-05-19 | — | — | WO | disclosed |
| EP-3967312-A1 | ANTIBACTERIAL USE OF HALOGENATED SALICYLANILIDES | UNION therapeutics A/S (DK) | 2022-03-16 | — | — | EP | disclosed |
| EP-3302492-B1 | HALOGENATED SALICYLANILIDES FOR TREATING CLOSTRIDIUM INFECTIONS | UNION THERAPEUTICS AS (DK) | 2021-03-17 | — | — | EP | disclosed |
| EP-3429691-B1 | NON-AQUEOUS TOPICAL COMPOSITIONS COMPRISING A HALOGENATED SALICYLANILIDE | UNION THERAPEUTICS AS (DK) | 2020-11-04 | — | — | EP | disclosed |
| WO-2020039073-A1 | HALOGENATED SALICYLANILIDES FOR THE TREATMENT OF DERMATITIS | UNION therapeutics A/S (DK) | 2020-02-27 | — | — | WO | disclosed |