Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080 | 0.97 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA | |
| SCHEMBL29349628 | 0.97 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA | |
| SCHEMBL29016490 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA | |
| SCHEMBL29798224 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA | |
| Ammonia Solution, Strong SCHEMBL7412270 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA | |
| SCHEMBL28038463 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA | |
| SCHEMBL10356935 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA | |
| Acetonitrile SCHEMBL2818707 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA | |
| SCHEMBL31645911 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA | |
| SCHEMBL28883610 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1CHRM2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973172-B2 | Organic compound, semiconductor film electrode employing the organic compound, photoelectric conversion element employing the organic compound, and photoelectrochemical solar cell employing the organic compound | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20100174095-A1 | ORGANIC COMPOUND, SEMICONDUCTOR FILM ELECTRODE EMPLOYING THE ORGANIC COMPOUND, PHOTOELECTRIC CONVERSION ELEMENT EMPLOYING THE ORGANIC COMPOUND, AND PHOTOELECTROCHEMICAL SOLAR CELL EMPLOYING THE ORGANIC COMPOUND | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174095-A1 | ORGANIC COMPOUND, SEMICONDUCTOR FILM ELECTRODE EMPLOYING THE ORGANIC COMPOUND, PHOTOELECTRIC CONVERSION ELEMENT EMPLOYING THE ORGANIC COMPOUND, AND PHOTOELECTROCHEMICAL SOLAR CELL EMPLOYING THE ORGANIC COMPOUND | HCN3, HCN4, HCN2 | SMN1; SMN2 4278/4885L3MBTL1 3996/4885CHRM2 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.