Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349628 | 0.91 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1AHRCHRM2LMNA | |
| SCHEMBL29080 | 0.91 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1AHRCHRM2LMNA | |
| Iodide SCHEMBL2177798 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRCHRM2LMNA | |
| SCHEMBL29016490 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRCHRM2LMNA | |
| SCHEMBL29798224 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRCHRM2LMNA | |
| Ammonia Solution, Strong SCHEMBL7412270 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRCHRM2LMNA | |
| Acetonitrile SCHEMBL2818707 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM2LMNA | |
| SCHEMBL27404111 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1AHRLMNAKDM4E | |
| Trifluoromethanesulfonic Acid SCHEMBL6282631 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1AHRLMNAKDM4E | |
| SCHEMBL15160582 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1AHRCHRM2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189507-A | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN LTD | 2015-12-23 | — | — | CN | disclosed |