Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28576310 | 0.77 | PDPK1 (0.45) | PDPK1ALOX5MEN1KMT2AGRM5 | |
| SCHEMBL2696934 | 0.74 | PDPK1 (0.42) | PDPK1ALOX5MEN1KMT2AGRM5 | |
| SCHEMBL1255675 | 0.74 | PDPK1 (0.42) | PDPK1ALOX5MEN1KMT2AGRM5 | |
| SCHEMBL150158 | 0.73 | TAAR1 (0.56) | TAAR1LOXL2KCNN4ALDH1A1TSHR | |
| SCHEMBL27648862 | 0.71 | TAAR1 (0.54) | TAAR1LOXL2KCNN4ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL7564407 | 0.71 | TAAR1 (0.54) | TAAR1LOXL2KCNN4ALDH1A1TSHR | |
| SCHEMBL7523537 | 0.71 | TAAR1 (0.54) | TAAR1LOXL2KCNN4ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29030881 | 0.71 | TAAR1 (0.54) | TAAR1LOXL2KCNN4ALDH1A1TSHR | |
| SCHEMBL4639357 | 0.71 | ALOX5 (0.37) | ALOX5NR1H2 | |
| SCHEMBL17504076 | 0.70 | PDPK1 (0.39) | PDPK1ALOX5MEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3843724-A1 | BENZIMIDAZOLE COMPOUNDS AND USE THEREOF FOR TREATING ALZHEIMER'S DISEASE OR HUNTINGTON'S DISEASE | National Health Research Institutes (TW) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020047360-A1 | BENZIMIDAZOLE COMPOUNDS AND USE THEREOF FOR TREATING ALZHEIMER'S DISEASE OR HUNTINGTON'S DISEASE | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2020-03-05 | — | — | WO | disclosed |