Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 5/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1184438 | 0.78 | CETP (0.41) | ALOX5CETPVNN1 | |
| SCHEMBL4640356 | 0.78 | NOS3 (0.39) | CETPKIF11VNN1 | |
| SCHEMBL10202789 | 0.75 | CETP (0.47) | CETPVNN1 | |
| SCHEMBL4639184 | 0.72 | CETP (0.52) | CETP | |
| SCHEMBL4968059 | 0.71 | KIF11 (0.38) | TACR1CETPKIF11 | |
| SCHEMBL21778110 | 0.71 | PDPK1 (0.40) | ALOX5NR1H2 | |
| SCHEMBL4639381 | 0.70 | KIF11 (0.44) | CETPKIF11 | |
| SCHEMBL4639666 | 0.69 | TACR1 (0.35) | TACR1CETPKIF11 | |
| SCHEMBL4639707 | 0.68 | GPBAR1 (0.36) | TACR1CETPKIF11 | |
| SCHEMBL1183378 | 0.68 | CETP (0.66) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951673-A2 | HETEROCYCLIC CETP INHIBITORS | Bristol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |