Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CASP1 | P29466 | 2/20 | 0.30 |
| ▸ | CASP7 | P55210 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998258 | 0.86 | NPC1 (0.48) | L3MBTL1KDM4EATMNPSR1ALDH1A1 | |
| SCHEMBL12026167 | 0.86 | NPC1 (0.48) | L3MBTL1KDM4EATMNPSR1ALDH1A1 | |
| SCHEMBL21778195 | 0.85 | L3MBTL1 (0.43) | L3MBTL1KDM4EATMNPSR1ALDH1A1 | |
| SCHEMBL21778197 | 0.85 | L3MBTL1 (0.48) | L3MBTL1KDM4EATMALDH1A1NPC1 | |
| SCHEMBL21778191 | 0.85 | L3MBTL1 (0.53) | L3MBTL1KDM4EATMALDH1A1NPC1 | |
| SCHEMBL21778201 | 0.84 | L3MBTL1 (0.44) | L3MBTL1KDM4EATMALDH1A1NPC1 | |
| SCHEMBL21778196 | 0.81 | L3MBTL1 (0.41) | L3MBTL1KDM4EATMALDH1A1NPC1 | |
| SCHEMBL21778198 | 0.80 | L3MBTL1 (0.40) | L3MBTL1KDM4EATMALDH1A1NPC1 | |
| SCHEMBL15698272 | 0.79 | KDM4E (0.61) | L3MBTL1KDM4EATMNPSR1ALDH1A1 | |
| SCHEMBL12433925 | 0.79 | KDM4E (0.61) | L3MBTL1KDM4EATMNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577325-B2 | Method for preparing a series of carbazole derivatives and use thereof in organic light-emitting diodes | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2020-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577325-B2 | Method for preparing a series of carbazole derivatives and use thereof in organic light-emitting diodes | CYBA, PPOX, IK | L3MBTL1 431/4885KDM4E 2154/4885ATM 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.