Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779869 | 0.95 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1TSHRCYP3A4RAB9A | |
| SCHEMBL21514117 | 0.79 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1TSHRCYP3A4RAB9A | |
| SCHEMBL16254584 | 0.77 | POLB (0.47) | ALDH1A1L3MBTL1TSHRMAPK1CYP2D6 | |
| SCHEMBL25093395 | 0.75 | CYP2D6 (0.60) | ALDH1A1L3MBTL1TSHRCYP3A4RAB9A | |
| SCHEMBL14276927 | 0.75 | EPHX2 (0.70) | ALDH1A1L3MBTL1TSHRCYP3A4RAB9A | |
| SCHEMBL25093271 | 0.75 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1TSHRCYP3A4RAB9A | |
| SCHEMBL24202656 | 0.73 | MAPT (0.64) | ALDH1A1L3MBTL1TSHRCYP3A4RAB9A | |
| SCHEMBL24383487 | 0.73 | MAPT (0.64) | ALDH1A1L3MBTL1TSHRCYP3A4RAB9A | |
| SCHEMBL25123271 | 0.73 | MAPT (0.64) | ALDH1A1L3MBTL1TSHRCYP3A4RAB9A | |
| SCHEMBL24383446 | 0.73 | MAPT (0.64) | ALDH1A1L3MBTL1TSHRCYP3A4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3616753-A1 | COMPOUNDS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |