Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CD74 | P04233 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069322 | 0.92 | KMO (0.67) | KMORXRARXRBNPC1RAB9A | |
| SCHEMBL30526004 | 0.89 | KMO (0.75) | KMORXRARXRBNPC1RAB9A | |
| SCHEMBL21887690 | 0.86 | NPC1 (0.60) | NPC1RAB9AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL21760743 | 0.86 | NPC1 (0.60) | NPC1RAB9AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29904703 | 0.84 | KMO (0.80) | KMORXRARXRBRXRGGAA | |
| SCHEMBL69066 | 0.84 | KMO (0.80) | KMORXRARXRBRXRGGAA | |
| SCHEMBL10768172 | 0.84 | KMO (0.80) | KMORXRARXRBRXRGGAA | |
| SCHEMBL3551496 | 0.84 | KMO (0.80) | KMORXRARXRBRXRGGAA | |
| SCHEMBL1975452 | 0.84 | TSHR (0.63) | RXRARXRBNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL17667154 | 0.82 | KMO (0.77) | KMORXRARXRBRXRGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519467-A1 | MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF | Colorado State University Research Foundation (US) | 2012-11-07 | — | — | EP | claimed |
| WO-2011082164-A1 | MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-07-07 | — | — | WO | claimed |