SCHEMBL3551496

SCHEMBL3551496

O=C(O)c1ccc(-c2ccc(C(=O)O)cc2)cc1.O=C(O)c1ccc(-c2cccc(C(=O)O)c2)cc1

nearest known ligand 0.83

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.80
TRIM24 O15164 1/20 0.65
TRIM33 Q9UPN9 1/20 0.65
LMNA P02545 1/20 0.64
GAA P10253 1/20 0.64
RXRA P19793 6/20 0.63
RXRB P28702 6/20 0.63
RXRG P48443 1/20 0.62
BCL2 P10415 1/20 0.62
EGFR P00533 1/20 0.60
ERN1 O75460 1/20 0.59
EPHX2 P34913 1/20 0.58
NR1H4 Q96RI1 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69066 1.00 KMO (0.80) KMOTRIM24TRIM33LMNAGAA
SCHEMBL10768172 1.00 KMO (0.80) KMOTRIM24TRIM33LMNAGAA
SCHEMBL29904703 1.00 KMO (0.80) KMOTRIM24TRIM33LMNAGAA
Hydrochloric Acid SCHEMBL17667154 0.98 KMO (0.77) KMOTRIM24TRIM33LMNAGAA
Hydrochloric Acid SCHEMBL9718649 0.98 KMO (0.77) KMOTRIM24TRIM33LMNAGAA
SCHEMBL16166225 0.96 KMO (0.81) KMOTRIM24TRIM33LMNAGAA
SCHEMBL14683877 0.96 KMO (0.87) KMOTRIM24TRIM33LMNAGAA
SCHEMBL29577419 0.96 KMO (0.87) KMOTRIM24TRIM33LMNAGAA
SCHEMBL3220396 0.93 KMO (0.91) KMOTRIM24TRIM33LMNAGAA
SCHEMBL437537 0.93 KMO (0.91) KMOLMNAGAARXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-B1 POLYARYLATE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2009-08-26 EP claimed
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
US-7855241-B2 Method of improving abrasion resistance of plastic article using nanoparticles and article produced thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-12-21 US disclosed
EP-1763560-B1 POLYARYLATE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2009-08-26 EP disclosed
US-7576140-B2 Via thermoplastic polycarbonates, polyestercarbonates, and cyclic polysiloxanes SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-08-18 US disclosed
US-7557174-B2 Carboxy-terminated oligomeric polyester compositions and method for making SABIC INNOVATIVE PLASTICS IP BV (NL) 2009-07-07 US disclosed
EP-1951791-A2 METHOD OF IMPROVING ABRASION RESISTANCE OF PLASTIC ARTICLE AND ARTICLE PRODUCED THEREBY General Electric Company (US) 2008-08-06 EP disclosed
EP-1945695-A2 METHOD OF IMPROVING ABRASION RESISTANCE OF PLASTIC ARTICLE USING NANOPARTICLES AND ARTICLE PRODUCED THEREBY General Electric Company (US) 2008-07-23 EP disclosed
EP-1833872-A1 CARBOXY-TERMINATED OLIGOMERIC POLYESTER COMPOSITIONS AND METHOD FOR MAKING General Electric Company (US) 2007-09-19 EP disclosed
US-20070088095-A1 Method of improving abrasion resistance of plastic article using nanoparticles and article produced thereby GENERAL ELECTRIC COMPANY (US) 2007-04-19 US disclosed
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP disclosed
US-20070027290-A1 Carboxy-terminated oligomeric polyester compositions and method for making SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-02-01 US disclosed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US disclosed
WO-2006057810-A1 CARBOXY-TERMINATED OLIGOMERIC POLYESTER COMPOSITIONS AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY (US) 2006-06-01 WO disclosed
US-20060116487-A1 Carboxy-terminated oligomeric polyester compositions and method for making GENERAL ELECTRIC COMPANY 2006-06-01 US disclosed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO disclosed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US disclosed