Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 7/20 | 0.31 |
| ▸ | LTA4H | P09960 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780498 | 0.86 | HRH3 (0.36) | AXLSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL14480859 | 0.86 | HRH3 (0.36) | AXLSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL14480747 | 0.86 | HRH3 (0.36) | AXLSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL14480898 | 0.82 | HRH3 (0.37) | AXLSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL21780459 | 0.82 | HRH3 (0.37) | AXLSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL14480767 | 0.82 | HRH3 (0.37) | AXLSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL21780490 | 0.80 | HRH3 (0.37) | AXLSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL14480765 | 0.80 | HRH3 (0.37) | AXLSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL14480503 | 0.80 | HRH3 (0.37) | AXLSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL21780418 | 0.78 | HTR2A (0.41) | AXLSCN1ASCN4AKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085696-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-03-04 | — | — | EP | disclosed |