Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231845 | 0.84 | GRM5 (0.47) | ADORA2ASLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL506497 | 0.79 | ALDH1A1 (0.55) | ADORA2APLAUPDGFRBPDGFRAL3MBTL1 | |
| SCHEMBL8371346 | 0.79 | PLAU (0.44) | ADORA2APLAUPDGFRBPDGFRAL3MBTL1 | |
| SCHEMBL22957763 | 0.77 | RIPK1 (0.43) | — | |
| SCHEMBL29636120 | 0.77 | PLAU (0.43) | ADORA2AMAOAMAOBPLAUPDGFRB | |
| SCHEMBL10375020 | 0.77 | PLAU (0.43) | ADORA2AMAOAMAOBPLAUPDGFRB | |
| Hydrochloric Acid SCHEMBL11095592 | 0.77 | ALDH1A1 (0.53) | ADORA2APLAUPDGFRBPDGFRAL3MBTL1 | |
| SCHEMBL4475474 | 0.77 | PLAU (0.47) | ADORA2APLAUPDGFRBPDGFRAL3MBTL1 | |
| SCHEMBL507177 | 0.77 | PLAU (0.43) | ADORA2AMAOAMAOBPLAUPDGFRB | |
| SCHEMBL8497269 | 0.77 | PLAU (0.43) | ADORA2APLAUPDGFRBPDGFRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085696-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-03-04 | — | — | EP | disclosed |