Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14480723 | 0.75 | CA12 (0.42) | CA12CA9SCN5ASCN1ASCN4A | |
| SCHEMBL22563247 | 0.74 | CA12 (0.41) | CA12CA9SCN5ASCN1ASCN4A | |
| SCHEMBL29805916 | 0.73 | FABP6 (0.56) | CA12CA9SCN5ASCN1ASCN4A | |
| SCHEMBL14480649 | 0.73 | FABP6 (0.56) | CA12CA9SCN5ASCN1ASCN4A | |
| SCHEMBL22563264 | 0.72 | CA12 (0.40) | CA12CA9SCN5ASCN1ASCN4A | |
| SCHEMBL14480828 | 0.72 | CA12 (0.48) | CA12CA9SCN5ASCN1ASCN4A | |
| SCHEMBL21780434 | 0.72 | KCNH2 (0.46) | CA12CA9SCN5ASCN1ASCN4A | |
| SCHEMBL14481253 | 0.68 | KCNH2 (0.54) | CA12CA9SCN5ASCN1ASCN4A | |
| SCHEMBL807159 | 0.66 | ABL1 (0.38) | SCN5ASCN1ASCN4AKCNH2SCN9A | |
| SCHEMBL30966000 | 0.66 | GRM5 (0.50) | CA12CA9SCN5ASCN1ASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085696-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-03-04 | — | — | EP | disclosed |