Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31071972 | 0.79 | PDE4D (0.35) | PGK1KDM4EPDCD1LG2CD274ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31071938 | 0.77 | HTR2A (0.33) | PGK1 | |
| SCHEMBL25087901 | 0.75 | KMT2A (0.33) | KDM4EALDH1A1 | |
| SCHEMBL21767736 | 0.75 | NPC1 (0.40) | KDM4EHSP90AA1HSP90AB1PDCD1LG2CD274 | |
| SCHEMBL21780623 | 0.75 | HTR2A (0.36) | — | |
| SCHEMBL31071988 | 0.75 | NPC1 (0.40) | KDM4EHSP90AA1HSP90AB1PDCD1LG2CD274 | |
| SCHEMBL21780640 | 0.75 | HTR2A (0.36) | — | |
| SCHEMBL5058833 | 0.74 | ALDH1A1 (0.41) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL21767605 | 0.74 | HTR2A (0.35) | — | |
| Hydrochloric Acid SCHEMBL31072021 | 0.74 | HTR2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617206-A1 | INTEGRIN INHIBITORS | Morphic Therapeutic, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |