Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780623 | 1.00 | HTR2A (0.36) | HTR2ASLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL21767605 | 0.98 | HTR2A (0.35) | HTR2ASLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL31072021 | 0.98 | HTR2A (0.35) | HTR2ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL28566097 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL21767489 | 0.77 | TAS1R3 (0.41) | — | |
| SCHEMBL21780625 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL21780641 | 0.75 | PGK1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL31071938 | 0.75 | HTR2A (0.33) | HTR2ATAAR1 | |
| SCHEMBL22734130 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL31072039 | 0.73 | ABCB1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617206-A1 | INTEGRIN INHIBITORS | Morphic Therapeutic, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |