Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928219 | 0.83 | CHRM2 (0.58) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL14668122 | 0.81 | CHRM2 (0.59) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL1442239 | 0.81 | TAAR1 (0.62) | CHRM2CHRM1CHRM3TAAR1SIGMAR1 | |
| SCHEMBL21002162 | 0.80 | TAAR1 (0.71) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL29986862 | 0.80 | TAAR1 (0.71) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL21002016 | 0.80 | TAAR1 (0.71) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL21002124 | 0.78 | TAAR1 (0.69) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL27339567 | 0.77 | CHRM2 (0.55) | CHRM2CHRM1CHRM3TAAR1MTNR1A | |
| SCHEMBL723511 | 0.76 | TAAR1 (0.77) | CHRM2CHRM1CHRM3TAAR1SIGMAR1 | |
| SCHEMBL30080050 | 0.76 | TAAR1 (0.77) | CHRM2CHRM1CHRM3TAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092719-A2 | PROCESS FOR THE PREPARATION OF L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-08-04 | — | — | WO | disclosed |
| WO-2011080756-A1 | PROCESS FOR THE PREPARATION OF 1-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |