Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775202 | 0.85 | LMNA (0.36) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL20132590 | 0.83 | LMNA (0.32) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL178422 | 0.79 | — | — | |
| SCHEMBL13020901 | 0.79 | — | — | |
| SCHEMBL26205525 | 0.78 | LMNA (0.32) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL19074199 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL25280389 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL25280388 | 0.76 | — | — | |
| SCHEMBL19114630 | 0.76 | TSHR (0.33) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL13999449 | 0.73 | ALDH1A1 (0.40) | TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2909197-B1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | ASTEX THERAPEUTICS LTD (GB) | 2020-03-04 | — | — | EP | disclosed |