Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520126 | 0.89 | MGLL (0.54) | MGLLSMN1; SMN2HPGDGAANPSR1 | |
| SCHEMBL20802043 | 0.89 | MGLL (0.54) | MGLLSMN1; SMN2HPGDGAANPSR1 | |
| SCHEMBL26895628 | 0.88 | MGLL (0.51) | MGLLSMN1; SMN2HPGDGAANPSR1 | |
| SCHEMBL22109578 | 0.80 | MGLL (0.43) | MGLL | |
| SCHEMBL10173317 | 0.79 | MGLL (0.62) | MGLLSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL25579882 | 0.79 | MGLL (0.62) | MGLLSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL14968555 | 0.78 | MGLL (0.44) | MGLL | |
| SCHEMBL23506482 | 0.78 | PTGS1 (0.41) | MGLLSMN1; SMN2HPGDGAANPSR1 | |
| SCHEMBL27269360 | 0.78 | MGLL (0.56) | MGLLSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL30193481 | 0.78 | MGLL (0.57) | MGLLSMN1; SMN2HPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229844-B1 | ANTIBODY DRUG CONJUGATES WITH CELL PERMEABLE BCL-XL INHIBITORS | ABBVIE INC (US) | 2020-03-04 | — | — | EP | disclosed |