Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520126 | 0.99 | MGLL (0.54) | MGLLPTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL20802043 | 0.99 | MGLL (0.54) | MGLLPTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL21780896 | 0.88 | MGLL (0.54) | MGLLPTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL26707209 | 0.87 | MGLL (0.57) | MGLLPTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL30193481 | 0.87 | MGLL (0.57) | MGLLPTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL24240484 | 0.86 | MGLL (0.40) | MGLLPTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL23506482 | 0.85 | PTGS1 (0.41) | MGLLPTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL14968555 | 0.84 | MGLL (0.44) | MGLL | |
| SCHEMBL24476267 | 0.84 | MGLL (0.46) | MGLLPTGS1PTGS2HPGDALDH1A1 | |
| SCHEMBL26875609 | 0.84 | MGLL (0.46) | MGLLPTGS1PTGS2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225320-A1 | EPHA2 BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | NOVARTIS AG (CH) | 2023-11-23 | — | — | WO | disclosed |