Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15883613 | 0.79 | BCHE (0.54) | GRM5BCHE | |
| SCHEMBL847028 | 0.77 | BCHE (0.72) | BCHE | |
| SCHEMBL847712 | 0.77 | BCHE (0.72) | BCHE | |
| SCHEMBL21158406 | 0.75 | BCHE (0.50) | GRM5BCHE | |
| SCHEMBL18399575 | 0.75 | BCHE (0.50) | GRM5BCHE | |
| SCHEMBL20368692 | 0.75 | BCHE (0.50) | GRM5BCHE | |
| SCHEMBL21781670 | 0.72 | ALDH1A1 (0.38) | BCHE | |
| SCHEMBL2706554 | 0.72 | ERN1 (0.42) | — | |
| SCHEMBL21781486 | 0.71 | ALDH1A1 (0.37) | — | |
| SCHEMBL19059694 | 0.70 | BCHE (0.46) | GRM5BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945939-B1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE HOLDINGS CORP (US) | 2020-03-04 | — | — | EP | disclosed |