Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.37 |
| ▸ | FURIN | P09958 | 5/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21781878 | 0.94 | MAP1LC3B (0.37) | MAP1LC3BFURINKLKB1HTTHRH1 | |
| SCHEMBL21781879 | 0.93 | MAP1LC3B (0.37) | MAP1LC3BFURINKLKB1HTTHRH1 | |
| SCHEMBL22068145 | 0.84 | C3AR1 (0.36) | FURINKMT2A | |
| SCHEMBL29284569 | 0.84 | NPC1 (0.41) | MAP1LC3BHTTSMN1; SMN2KMT2A | |
| SCHEMBL22068492 | 0.83 | MAP1LC3B (0.36) | MAP1LC3BFURINKLKB1HRH1FAP | |
| SCHEMBL17312902 | 0.82 | FURIN (0.41) | MAP1LC3BFURINHTTSMN1; SMN2KMT2A | |
| SCHEMBL22068096 | 0.82 | NPC1 (0.41) | MAP1LC3BHTTSMN1; SMN2KMT2A | |
| SCHEMBL26223125 | 0.81 | FURIN (0.42) | FURINKLKB1HTTSMN1; SMN2NPY1R | |
| SCHEMBL21607790 | 0.81 | FURIN (0.42) | FURINKLKB1HTTSMN1; SMN2NPY1R | |
| SCHEMBL24270749 | 0.81 | FURIN (0.43) | FURINHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11207420-B2 | Cytotoxin and conjugate, uses of same and preparation method therefor | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20200179529-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME AND PREPARATION METHOD THEREFOR | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11207420-B2 | Cytotoxin and conjugate, uses of same and preparation method therefor | CD2, HAVCR2, CD4 | MAP1LC3B 1411/4885FURIN 676/4885KLKB1 408/4885 |
| US-20200179529-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME AND PREPARATION METHOD THEREFOR | CD2, HAVCR2, CD4 | MAP1LC3B 1411/4885FURIN 676/4885KLKB1 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.