Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.37 |
| ▸ | FURIN | P09958 | 5/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | NPY4R | P50391 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21781876 | 0.94 | MAP1LC3B (0.37) | MAP1LC3BFURINEHMT2HTTSMN1; SMN2 | |
| SCHEMBL21781879 | 0.92 | MAP1LC3B (0.37) | MAP1LC3BFURINEHMT2HTTSMN1; SMN2 | |
| SCHEMBL29284547 | 0.84 | NPC1 (0.41) | MAP1LC3BHTTSMN1; SMN2KMT2A | |
| SCHEMBL22068145 | 0.84 | C3AR1 (0.36) | FURINKMT2A | |
| SCHEMBL17595585 | 0.78 | FURIN (0.44) | FURINHTTSMN1; SMN2KMT2A | |
| SCHEMBL17595587 | 0.78 | FURIN (0.44) | FURINHTTSMN1; SMN2KMT2A | |
| SCHEMBL29284586 | 0.78 | NPC1 (0.41) | MAP1LC3BHTTSMN1; SMN2KMT2A | |
| SCHEMBL29284569 | 0.78 | NPC1 (0.41) | MAP1LC3BHTTSMN1; SMN2KMT2A | |
| SCHEMBL29284585 | 0.78 | MAP1LC3B (0.40) | MAP1LC3BFURINHTTFAPHRH1 | |
| SCHEMBL20513041 | 0.77 | HTT (0.44) | FURINHTTKMT2ANPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |