Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP4 | Q02790 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | FCER2 | P06734 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 4/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21781988 | 0.92 | KDM1A (0.41) | FKBP4KDM1AKMT2AAKT1KLKB1 | |
| SCHEMBL22561364 | 0.87 | KDM1A (0.39) | FKBP4KDM1AKMT2AAKT1KLKB1 | |
| SCHEMBL21781778 | 0.85 | KLKB1 (0.40) | FKBP4KDM1AKMT2AAKT1KLKB1 | |
| SCHEMBL22561427 | 0.84 | KLKB1 (0.44) | FKBP4KMT2AKLKB1MEN1MMP1 | |
| SCHEMBL21781776 | 0.83 | CXCR4 (0.38) | FKBP4KDM1AAKT1MMP1MMP3 | |
| SCHEMBL21781926 | 0.81 | AKT1 (0.42) | AKT1KLKB1LCKTACR2 | |
| SCHEMBL20750962 | 0.76 | GAA (0.41) | FKBP4TSHRTACR2 | |
| SCHEMBL22810961 | 0.75 | POLB (0.49) | KMT2A | |
| SCHEMBL21699252 | 0.75 | POLB (0.49) | KMT2A | |
| SCHEMBL2734908 | 0.75 | POLB (0.49) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |