Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864445 | 0.85 | CASP2 (0.52) | CASP2ALDH1A1SMN1; SMN2NAAASLC6A5 | |
| SCHEMBL1940161 | 0.82 | CASP2 (0.54) | CASP2ALDH1A1SMN1; SMN2NAAASLC6A5 | |
| SCHEMBL14620924 | 0.80 | SLC6A5 (0.43) | CASP2ALDH1A1SMN1; SMN2NAAASLC6A5 | |
| SCHEMBL9307257 | 0.79 | PRMT1 (0.55) | CASP2ALDH1A1SMN1; SMN2NAAAPRMT1 | |
| SCHEMBL19113233 | 0.79 | PRMT1 (0.55) | CASP2ALDH1A1SMN1; SMN2NAAAPRMT1 | |
| SCHEMBL25666251 | 0.78 | KMT2A (0.40) | ALDH1A1FAAHMEN1KMT2AHDAC3 | |
| SCHEMBL13819838 | 0.78 | CASP2 (0.60) | CASP2NAAASLC6A5FAAHDNM1 | |
| SCHEMBL27318015 | 0.78 | PRMT1 (0.59) | CASP2ALDH1A1SMN1; SMN2PRMT1EPHX2 | |
| SCHEMBL24712683 | 0.77 | HDAC3 (0.54) | CASP2ALDH1A1SMN1; SMN2NAAASLC6A5 | |
| SCHEMBL20783724 | 0.76 | PAOX (0.50) | CASP2ALDH1A1SMN1; SMN2NAAASLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3249049-B1 | COMPOUNDS AND METHODS FOR DETECTION OF ENZYMES THAT REMOVE SUCCINYL OR METHYL SUCCINYL GROUPS FROM EPSILON AMINO LYSINE MOIETIES | ENZO LIFE SCIENCES INC (US) | 2020-03-04 | — | — | EP | disclosed |