Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782563 | 1.00 | HDAC3 (0.35) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL21782560 | 1.00 | HDAC3 (0.35) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL13867554 | 0.93 | — | — | |
| SCHEMBL5219364 | 0.78 | HTT (0.41) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL11955648 | 0.78 | HTT (0.41) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL14627310 | 0.78 | HTT (0.41) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL5260246 | 0.78 | HTT (0.41) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL1694483 | 0.78 | CNR2 (0.37) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20502497 | 0.76 | HTT (0.40) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL11272873 | 0.76 | HDAC3 (0.35) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617195-A1 | NOVEL TETRAHYDRONAPHTHYL UREA DERIVATIVES | Mochida Pharmaceutical Co., Ltd. (JP) | 2020-03-04 | — | — | EP | disclosed |