Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975659 | 0.88 | TDP1 (0.50) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL16217782 | 0.88 | TDP1 (0.50) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL5024804 | 0.88 | MEN1 (0.55) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL16263593 | 0.87 | TDP1 (0.49) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL8075065 | 0.86 | MEN1 (0.56) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL8602068 | 0.86 | TDP1 (0.48) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL15976620 | 0.86 | MEN1 (0.55) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL12192757 | 0.86 | CTSS (0.51) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL31206803 | 0.86 | TDP1 (0.48) | TDP1ATMMEN1KMT2AGAA | |
| SCHEMBL16504664 | 0.86 | CTSS (0.53) | TDP1ATMMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753613-B1 | DERIVATIVES OF XANTHONE COMPOUNDS | AGENCY SCIENCE TECH & RES (SG) | 2020-03-04 | — | — | EP | disclosed |