SCHEMBL5024804

SCHEMBL5024804

COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
GAA P10253 1/20 0.55
TDP1 Q9NUW8 6/20 0.54
ATM Q13315 2/20 0.54
NPSR1 Q6W5P4 4/20 0.52
POLB P06746 3/20 0.52
MAPT P10636 2/20 0.49
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CA12 O43570 2/20 0.49
CA9 Q16790 2/20 0.49
CTSK P43235 2/20 0.48
CTSS P25774 1/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
KLK7 P49862 1/20 0.46
KLK5 Q9Y337 1/20 0.46
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14820488 0.96 TDP1 (0.50) MEN1KMT2AGAATDP1ATM
SCHEMBL30186579 0.95 MEN1 (0.60) MEN1KMT2AGAATDP1ATM
SCHEMBL16505182 0.95 CTSS (0.53) MEN1KMT2AGAATDP1ATM
SCHEMBL16217782 0.95 TDP1 (0.50) MEN1KMT2AGAATDP1ATM
SCHEMBL16505181 0.95 CTSS (0.53) MEN1KMT2AGAATDP1ATM
SCHEMBL19975659 0.95 TDP1 (0.50) MEN1KMT2AGAATDP1ATM
SCHEMBL16504665 0.95 CTSS (0.53) MEN1KMT2AGAATDP1ATM
SCHEMBL16505183 0.95 CTSS (0.53) MEN1KMT2AGAATDP1ATM
SCHEMBL16504664 0.95 CTSS (0.53) MEN1KMT2AGAATDP1ATM
SCHEMBL12262209 0.93 MEN1 (0.52) MEN1KMT2AGAATDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-10544434-B2 Process for the preparation of lisdexamfetamine and related derivatives NORAMCO, INC. (US) 2020-01-28 US disclosed
US-20180044304-A1 1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2018-02-15 US disclosed
WO-2016142852-A1 1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2016-09-15 WO disclosed
US-20100093811-A1 HIV PROTEASE INHIBITORS MERCK SHARP & DOHME CORP. 2010-04-15 US disclosed
US-7314940-B2 For therapy and prophylaxis of neurodegenerative disorders related to apoptosis and/or inflammation EISAI CO., LTD. (JP) 2008-01-01 US disclosed
EP-1373269-B1 JUN KINASE INHIBITORS EISAI CO LTD (JP) 2005-06-08 EP disclosed
US-20040235864-A1 Jun kinase inhibitors EISAI R & D MANAGEMENT CO., LTD. (JP) 2004-11-25 US disclosed
EP-1373269-A1 JUN KINASE INHIBITORS Eisai Co., Ltd. (JP) 2004-01-02 EP disclosed
WO-2002081475-A1 JUN KINASE INHIBITORS EISAI CO., LIMITED (JP) 2002-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10544434-B2 Process for the preparation of lisdexamfetamine and related derivatives COMT, MGAM, GAA MEN1 3423/4885KMT2A 1057/4885GAA 3/4885
US-20100093811-A1 HIV PROTEASE INHIBITORS PRSS1, FURIN, SERPINB1 MEN1 2771/4885KMT2A 1501/4885GAA 207/4885
US-20040235864-A1 Jun kinase inhibitors NFKBIA, JUN, AIFM1 MEN1 4674/4885KMT2A 3298/4885GAA 2165/4885
US-20180044304-A1 1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS PDCD1, CD274, PDCD1LG2 MEN1 3936/4885KMT2A 3330/4885GAA 3508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.