Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25022305 | 0.90 | TSHR (0.37) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL24589046 | 0.84 | TSHR (0.60) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL22455497 | 0.79 | TSHR (0.74) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL12456968 | 0.79 | TSHR (0.52) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL3390773 | 0.78 | HSD17B10 (0.36) | TSHRHSD17B10 | |
| SCHEMBL4653188 | 0.78 | TSHR (0.63) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL76380 | 0.78 | — | — | |
| SCHEMBL11193512 | 0.78 | TSHR (0.46) | TSHRHTTTHRBKMT2AUSP2 | |
| SCHEMBL223886 | 0.78 | TSHR (0.46) | TSHRHTTTHRBKMT2AUSP2 | |
| SCHEMBL15593359 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210108207-A1 | OLIGONUCLEOTIDE DERIVATIVE OR SALT THEREOF | KYOWA KIRIN CO., LTD. (JP) | 2021-04-15 | — | — | US | disclosed |
| EP-3617314-A1 | OLIGONUCLEOTIDE DERIVATIVE OR SALT THEREOF | Kyowa Kirin Co., Ltd. (JP) | 2020-03-04 | — | — | EP | disclosed |