Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782706 | 0.90 | TSHR (0.42) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL18506581 | 0.84 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL24589046 | 0.84 | TSHR (0.60) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL3390773 | 0.78 | HSD17B10 (0.36) | TSHRHSD17B10 | |
| SCHEMBL18866589 | 0.77 | HSD17B10 (0.32) | HSD17B10 | |
| SCHEMBL15593359 | 0.77 | — | — | |
| SCHEMBL22455497 | 0.75 | TSHR (0.74) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL2551087 | 0.74 | TSHR (0.50) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL578972 | 0.74 | TSHR (0.50) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL2323645 | 0.74 | TSHR (0.50) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617314-B1 | OLIGONUCLEOTIDE DERIVATIVE OR SALT THEREOF | KYOWA KIRIN CO LTD (JP) | 2023-02-15 | — | — | EP | disclosed |