Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704689 | 0.86 | GNAI3 (0.41) | KDM4ERAB9AGNAI3GNAO1GNAI1 | |
| SCHEMBL18520306 | 0.86 | ALDH1A1 (0.37) | KDM4EALDH1A1KDM1AMAPK1RAB9A | |
| SCHEMBL9881134 | 0.84 | PAOX (0.44) | ALDH1A1KDM1ARAB9ASIGMAR1 | |
| SCHEMBL18520145 | 0.81 | HRH3 (0.52) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL24132144 | 0.81 | — | — | |
| SCHEMBL6659406 | 0.80 | KDM1A (0.48) | KDM4EALDH1A1KDM1AMAPK1RAB9A | |
| SCHEMBL6663102 | 0.80 | GNAI3 (0.50) | KDM4EALDH1A1KDM1AMAPK1RAB9A | |
| SCHEMBL17209067 | 0.79 | HRH3 (0.56) | KDM4EALDH1A1MAPK1SIGMAR1 | |
| SCHEMBL6659172 | 0.78 | GNAI3 (0.54) | GNAI3GNAO1GNAI1 | |
| SCHEMBL25728743 | 0.77 | PIK3CD (0.41) | RAB9ASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50030-E1 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| EP-3333232-B1 | CHEMICAL MECHANICAL POLISHING COMPOSITION HAVING CHEMICAL ADDITIVES AND METHODS FOR USING | VERSUM MAT US LLC (US) | 2020-03-04 | — | — | EP | disclosed |