Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.78 |
| ▸ | BAG3 | O95817 | 1/20 | 0.68 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.60 |
| ▸ | MGAM | O43451 | 1/20 | 0.60 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SI | P14410 | 1/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28374956 | 1.00 | PPARG (0.78) | PPARGBAG3CISD1MEN1KMT2A | |
| SCHEMBL21783145 | 0.88 | PPARG (1.00) | PPARGBAG3MEN1KMT2AALDH1A1 | |
| SCHEMBL21783127 | 0.88 | PPARG (0.81) | PPARGBAG3MEN1KMT2AALDH1A1 | |
| SCHEMBL28374629 | 0.88 | PPARG (0.81) | PPARGBAG3MEN1KMT2AALDH1A1 | |
| SCHEMBL21783153 | 0.86 | PPARG (0.84) | PPARGBAG3MEN1KMT2AALDH1A1 | |
| SCHEMBL21783155 | 0.86 | MAPT (0.73) | PPARGBAG3MEN1KMT2AALDH1A1 | |
| SCHEMBL28373919 | 0.86 | MAPT (0.73) | PPARGBAG3MEN1KMT2AALDH1A1 | |
| SCHEMBL21783164 | 0.85 | PPARG (1.00) | PPARGBAG3MEN1KMT2AALDH1A1 | |
| SCHEMBL21783142 | 0.85 | PPARG (0.82) | PPARGBAG3MEN1KMT2AALDH1A1 | |
| SCHEMBL21783171 | 0.85 | PPARG (0.82) | PPARGBAG3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | DDC, ODC1, DDT | PPARG 3668/4885BAG3 4493/4885CISD1 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.