Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.57 |
| ▸ | BAG3 | O95817 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.54 |
| ▸ | ITGAM | P11215 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534482 | 1.00 | PPARG (0.64) | PPARGALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20534483 | 1.00 | PPARG (0.64) | PPARGALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21783128 | 0.90 | PPARG (0.67) | PPARGALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21783124 | 0.87 | CTNNB1 (0.67) | ALDH1A1KMT2ACTNNB1TCF7L2 | |
| SCHEMBL20534506 | 0.87 | CTNNB1 (0.67) | ALDH1A1KMT2ACTNNB1TCF7L2 | |
| SCHEMBL21783130 | 0.81 | AKR1B1 (0.72) | PPARGALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21783163 | 0.81 | PPARG (0.70) | PPARGALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20534277 | 0.80 | ALDH1A1 (0.76) | PPARGALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20534278 | 0.80 | ALDH1A1 (0.76) | PPARGALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21783127 | 0.79 | PPARG (0.81) | PPARGALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | DDC, ODC1, DDT | PPARG 3668/4885ALDH1A1 461/4885KMT2A 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.