Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GJB2 | P29033 | 1/20 | 0.34 |
| ▸ | FGF1 | P05230 | 2/20 | 0.33 |
| ▸ | FGF2 | P09038 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15095289 | 0.84 | LMNA (0.37) | BCHEACHECA1CA2CA9 | |
| SCHEMBL21783194 | 0.80 | BCHE (0.52) | BCHEACHEPDE4DPSEN1PSEN2 | |
| SCHEMBL21783250 | 0.80 | BCHE (0.47) | BCHEACHEPDE4DPSEN1PSEN2 | |
| SCHEMBL5788946 | 0.79 | CTSL (0.41) | BCHEACHECA1CA2CA9 | |
| SCHEMBL22798652 | 0.79 | BCHE (0.42) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL2647154 | 0.78 | CTSL (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL428528 | 0.78 | CTSL (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17443117 | 0.78 | CTSL (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL782454 | 0.77 | TAAR1 (0.34) | BCHEACHELMNA | |
| SCHEMBL782455 | 0.77 | TAAR1 (0.34) | BCHEACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046132-A1 | PHARMACOLOGICAL CHAPERONES FOR ENZYME TREATMENT THERAPY | LEIDEN UNIVERSITY (NL) | 2020-03-05 | — | — | WO | disclosed |