Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21074750 | 0.93 | KDM4E (0.42) | KCNH2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL23197067 | 0.81 | KCNH2 (0.43) | KCNH2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21074773 | 0.81 | KDM4E (0.48) | KCNH2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL15791569 | 0.78 | ALDH1A1 (0.48) | KCNH2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21783170 | 0.78 | KDM4E (0.43) | KCNH2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21074734 | 0.77 | KCNH2 (0.41) | KCNH2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21074631 | 0.73 | KDM4E (0.61) | KCNH2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21783222 | 0.72 | KDM4E (0.49) | KCNH2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21074708 | 0.70 | KDM4E (0.48) | KCNH2KDM4EALDH1A1HPGDLMNA | |
| Finafloxacin SCHEMBL7610665 | 0.69 | ALDH1A1 (0.54) | KCNH2KDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014269-A9 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2020-03-05 | — | — | WO | disclosed |