Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23197066 | 0.89 | LMNA (0.65) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL21783167 | 0.76 | HSD17B10 (0.55) | LMNAMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL21074647 | 0.75 | HSD17B10 (0.69) | LMNAMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL11035359 | 0.75 | LMNA (0.72) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL23197636 | 0.75 | LMNA (0.64) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL21074731 | 0.74 | LMNA (0.57) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL14176522 | 0.73 | LMNA (0.69) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL659309 | 0.73 | LMNA (0.69) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL18213620 | 0.71 | LMNA (0.65) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8044673 | 0.70 | LMNA (0.79) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014269-A9 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2020-03-05 | — | — | WO | disclosed |