Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21074647 | 0.90 | HSD17B10 (0.69) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL7878070 | 0.78 | HSD17B10 (0.73) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL21783166 | 0.77 | HSD17B10 (0.55) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL23197066 | 0.77 | LMNA (0.65) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL21074769 | 0.76 | HSD17B10 (0.69) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL10669929 | 0.76 | HSD17B10 (0.69) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL21783230 | 0.76 | LMNA (0.50) | HSD17B10KDM4EMEN1KMT2AHIF1A | |
| SCHEMBL29548937 | 0.76 | HSD17B10 (0.78) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL27397656 | 0.76 | HSD17B10 (0.78) | HSD17B10DRD3KDM4EMEN1KMT2A | |
| SCHEMBL19668774 | 0.75 | KDM4E (0.61) | HSD17B10DRD3KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014269-A9 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2020-03-05 | — | — | WO | disclosed |