Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783287 | 1.00 | NAAA (0.43) | NAAABCHEACHEPDE4DFFAR1 | |
| SCHEMBL477463 | 0.89 | TSHR (0.50) | NAAABCHEACHEPDE4DCTSL | |
| SCHEMBL477464 | 0.89 | TSHR (0.50) | NAAABCHEACHEPDE4DCTSL | |
| SCHEMBL598878 | 0.89 | TSHR (0.50) | NAAABCHEACHEPDE4DCTSL | |
| SCHEMBL16533210 | 0.86 | CTSL (0.50) | NAAACTSLCTSBCTSKTSHR | |
| SCHEMBL426503 | 0.86 | CTSL (0.50) | NAAACTSLCTSBCTSKTSHR | |
| SCHEMBL989536 | 0.86 | CTSL (0.50) | NAAACTSLCTSBCTSKTSHR | |
| Methoxymethane SCHEMBL967072 | 0.84 | CTSL (0.48) | NAAABCHEACHEPDE4DCTSL | |
| Methoxymethane SCHEMBL967074 | 0.84 | CTSL (0.48) | NAAABCHEACHEPDE4DCTSL | |
| Phosphoric Acid SCHEMBL599938 | 0.82 | TSHR (0.46) | NAAACTSLCTSBCTSKTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046132-A1 | PHARMACOLOGICAL CHAPERONES FOR ENZYME TREATMENT THERAPY | LEIDEN UNIVERSITY (NL) | 2020-03-05 | — | — | WO | disclosed |