Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783252 | 0.84 | BCHE (0.44) | BCHEACHEATMPDE4DPDPK1 | |
| SCHEMBL21783194 | 0.80 | BCHE (0.52) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL14697149 | 0.80 | BCHE (0.41) | BCHEACHEATMPDE4DPDPK1 | |
| SCHEMBL22729198 | 0.77 | KMT2A (0.52) | EPHX2KMT2A | |
| SCHEMBL22756279 | 0.77 | KMT2A (0.52) | EPHX2KMT2A | |
| SCHEMBL6290185 | 0.75 | LMNA (0.43) | BCHEACHEAGTR2EPHX2ALDH1A1 | |
| SCHEMBL2633999 | 0.75 | EPHX2 (0.51) | PDPK1MTORAGTR2EPHX2ALDH1A1 | |
| SCHEMBL2634094 | 0.75 | EPHX2 (0.51) | PDPK1MTORAGTR2EPHX2ALDH1A1 | |
| SCHEMBL21783250 | 0.75 | BCHE (0.47) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL21783181 | 0.74 | BCHE (0.46) | BCHEACHEPDE4DPDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046132-A1 | PHARMACOLOGICAL CHAPERONES FOR ENZYME TREATMENT THERAPY | LEIDEN UNIVERSITY (NL) | 2020-03-05 | — | — | WO | disclosed |