Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783527 | 0.81 | — | — | |
| SCHEMBL21783386 | 0.77 | SCN8A (0.33) | SSTR4 | |
| SCHEMBL30845678 | 0.77 | SCN8A (0.33) | SSTR4 | |
| SCHEMBL21783536 | 0.70 | SCN8A (0.33) | — | |
| SCHEMBL21783459 | 0.69 | SCN8A (0.32) | — | |
| SCHEMBL16638904 | 0.69 | SYK (0.36) | SSTR4 | |
| SCHEMBL28335538 | 0.69 | PAX8 (0.32) | SSTR4 | |
| SCHEMBL21783403 | 0.68 | QPCT (0.32) | — | |
| SCHEMBL19631663 | 0.67 | SCN8A (0.32) | SSTR4 | |
| SCHEMBL22331230 | 0.65 | SCN8A (0.35) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047312-A1 | HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS | XENON PHARMACEUTICALS INC. (CA) | 2020-03-05 | — | — | WO | disclosed |
| WO-2020047323-A1 | HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2020-03-05 | — | — | WO | disclosed |