Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 4/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334386 | 0.88 | ALDH1A1 (0.68) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 | |
| SCHEMBL20237531 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 | |
| SCHEMBL29668760 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 | |
| SCHEMBL20256796 | 0.82 | ALDH1A1 (0.65) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 | |
| Methylamine SCHEMBL20238761 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 | |
| SCHEMBL20238341 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 | |
| SCHEMBL10211855 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 | |
| SCHEMBL6803849 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 | |
| SCHEMBL807442 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 | |
| SCHEMBL3262128 | 0.78 | ALDH1A1 (0.96) | ALDH1A1KDM4EPOLBSMN1; SMN2CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047323-A1 | HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2020-03-05 | — | — | WO | disclosed |