Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783431 | 0.80 | SCN1A (0.32) | SCN1ASCN5ASCN8A | |
| SCHEMBL21783433 | 0.75 | SCN1A (0.37) | SCN1ASCN5ASCN8A | |
| SCHEMBL21783470 | 0.74 | SCN8A (0.51) | SCN1ASCN5ASCN8A | |
| Hydrochloric Acid SCHEMBL30045901 | 0.74 | SCN8A (0.51) | SCN1ASCN5ASCN8A | |
| Hydrochloric Acid SCHEMBL21955511 | 0.74 | SCN8A (0.51) | SCN1ASCN5ASCN8A | |
| Hydrochloric Acid SCHEMBL21955510 | 0.73 | SCN8A (0.50) | SCN1ASCN5ASCN8A | |
| SCHEMBL21794067 | 0.63 | ALDH1A1 (0.31) | — | |
| SCHEMBL23620157 | 0.62 | USP2 (0.32) | — | |
| SCHEMBL30991333 | 0.62 | USP2 (0.32) | — | |
| SCHEMBL19634337 | 0.60 | SCN1A (0.33) | SCN1ASCN5ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047323-A1 | HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2020-03-05 | — | — | WO | disclosed |