Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19332857 | 0.81 | PARP1 (0.44) | GRM5MEN1KMT2A | |
| SCHEMBL18067757 | 0.81 | HPGD (0.42) | GRM5NOTUM | |
| SCHEMBL4316519 | 0.79 | DRD2 (0.49) | GRM5MEN1KMT2A | |
| SCHEMBL29896985 | 0.77 | GRM5 (0.47) | GRM5MEN1KMT2A | |
| SCHEMBL6924020 | 0.77 | GRM5 (0.47) | GRM5MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29896869 | 0.76 | GRM5 (0.46) | GRM5MEN1KMT2A | |
| SCHEMBL12628111 | 0.73 | GRM5 (0.49) | GRM5NOTUM | |
| SCHEMBL19332797 | 0.73 | BACE1 (0.43) | GRM5NOTUM | |
| SCHEMBL10296104 | 0.72 | MEN1 (0.65) | GRM5MEN1KMT2A | |
| SCHEMBL2741632 | 0.72 | GRM5 (0.40) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046975-A1 | METHODS OF TREATING NEURODEGENERATIVE DISEASES | Seal Rock Therapeutics, Inc. (US) | 2020-03-05 | — | — | WO | disclosed |