Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496749 | 0.85 | ALDH1A1 (0.63) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21784390 | 0.80 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL880383 | 0.80 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21784398 | 0.80 | MEN1 (0.50) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17466933 | 0.79 | KMT2A (0.74) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28627982 | 0.79 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21784388 | 0.78 | MAPT (0.53) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7905288 | 0.75 | ALDH1A1 (0.69) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7905291 | 0.75 | ALDH1A1 (0.69) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7716072 | 0.75 | ALDH1A1 (0.69) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020044213-A1 | DIPHENYLAMINO-METHYLENE MALONONITRILE BASED COMPOUNDS AS FLUORESCENCE PROBES | UNIVERSITY OF HYDERABAD (IN) | 2020-03-05 | — | — | WO | disclosed |