SCHEMBL5496749

SCHEMBL5496749

N#CC(C#N)=Cc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.63
MAPT P10636 9/20 0.63
KMT2A Q03164 8/20 0.63
MEN1 O00255 7/20 0.63
KDM4E B2RXH2 4/20 0.63
NPSR1 Q6W5P4 2/20 0.63
LMNA P02545 2/20 0.63
POLB P06746 1/20 0.63
THRB P10828 1/20 0.55
CISD1 Q9NZ45 1/20 0.55
EGFR P00533 3/20 0.53
MAPK1 P28482 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
RAB9A P51151 1/20 0.49
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
HPGD P15428 2/20 0.49
TSHR P16473 2/20 0.49
NFKB1 P19838 2/20 0.49
BLM P54132 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL880383 0.93 MAPT (0.56) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL17466933 0.92 KMT2A (0.74) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL28627982 0.92 MAPT (0.54) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL21784392 0.85 MAPT (0.48) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL60843 0.82 MAPT (0.76) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL28621665 0.81 ALDH1A1 (0.47) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL7905291 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL7716072 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL7905288 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL9915843 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172272-B1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & CO (US) 2020-11-25 EP disclosed
CN-110518451-A The aggregation laser device and preparation method of temperature regulation and photoswitch application UNIV SOUTH CHINA TECH 2019-11-29 CN disclosed
CN-110518450-A The preparation method and photoinduction aggregation laser device of photoinduction aggregation laser device UNIV SOUTH CHINA TECH 2019-11-29 CN disclosed
US-9410035-B2 Modified heterophasic polyolefin composition MILLIKEN & COMPANY (US) 2016-08-09 US disclosed
US-20160024289-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY 2016-01-28 US disclosed
EP-1578884-B1 POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORP (JP) 2013-04-24 EP disclosed
EP-2261270-A1 Polymer, producing method thereof, and photorefractive composition Nitto Denko Corporation (JP) 2010-12-15 EP disclosed
EP-1594176-B1 SWITCHING DEVICE FUJI ELECTRIC HOLDINGS (JP) 2010-05-19 EP disclosed
US-7227178-B2 Switching element FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2007-06-05 US disclosed
US-7227178-B2 Switching element FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2007-06-05 US disclosed
CN-1901092-A Device comprising multiple bit data ROHM & HAAS ELECT MAT (US) 2007-01-24 CN disclosed
EP-1744322-A1 Devices containing multi-bit data Rohm and Haas Electronic Materials, L.L.C. (US) 2007-01-17 EP disclosed
US-20070009821-A1 Devices containing multi-bit data CUTLER CHARLOTTE 2007-01-11 US disclosed
EP-0868682-A1 ELECTRO- OR OPTO-OPTICAL DEVICE STABLE IN THE 600-1600 NANOMETER WAVELENGTH RANGE Akzo Nobel N.V. (NL) 1998-10-07 EP disclosed
US-5776375-A CONTAINING NONLINEAR OPTICALLY ACTIVE POLYMER AKZO NOBEL N.V. (NL) 1998-07-07 US disclosed
WO-1997023807-A1 ELECTRO- OR OPTO-OPTICAL DEVICE STABLE IN THE 600-1600 NANOMETER WAVELENGTH RANGE AKZO NOBEL N.V. (NL) 1997-07-03 WO disclosed
EP-0780722-A1 Electro-optical device stable in the 600-1600 nanometer wavelength range Akzo Nobel N.V. (NL) 1997-06-25 EP disclosed