Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31072018 | 0.80 | F2R (0.40) | F2RPKMMAPTTHRATHRB | |
| SCHEMBL21767653 | 0.80 | F2R (0.40) | F2RPKMMAPTTHRATHRB | |
| SCHEMBL21780541 | 0.78 | F2R (0.39) | F2RPKMMAPTTHRATHRB | |
| SCHEMBL26044824 | 0.78 | F2R (0.41) | F2RPKMMAPTTHRATHRB | |
| SCHEMBL21780538 | 0.75 | F2R (0.56) | F2RPKMMAPTTHRATHRB | |
| SCHEMBL5952920 | 0.72 | F2R (0.48) | F2RPKMMAPTTHRATHRB | |
| SCHEMBL21857955 | 0.70 | F2R (0.44) | F2RPKMMAPTMEN1LMNA | |
| SCHEMBL22097313 | 0.70 | PKM (0.49) | F2RPKMMAPTMEN1CYP1A2 | |
| SCHEMBL5777608 | 0.68 | TSHR (0.55) | F2RPKMMAPTMEN1LMNA | |
| SCHEMBL21858005 | 0.68 | F2R (0.40) | F2RPKMMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047239-A1 | INHIBITING αV β6 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2020-03-05 | — | — | WO | disclosed |