SCHEMBL21786017

SCHEMBL21786017

C=Cc1ccccc1/C=C/c1cccc2cc3ccccc3cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
MITF O75030 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
PKM P14618 1/20 0.50
MAPK1 P28482 1/20 0.50
RAB9A P51151 1/20 0.50
CCR6 P51684 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
KDM4E B2RXH2 2/20 0.38
GAA P10253 2/20 0.38
CHAT P28329 5/20 0.38
RXRA P19793 1/20 0.36
HIF1A Q16665 1/20 0.35
CYP1B1 Q16678 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29891468 0.90 ALDH1A1 (0.54) ALDH1A1MEN1MAPTKMT2AMITF
SCHEMBL27113 0.90 ALDH1A1 (0.54) ALDH1A1MEN1MAPTKMT2AMITF
Anthracene SCHEMBL28971423 0.90 ALDH1A1 (0.54) ALDH1A1MEN1MAPTKMT2AMITF
SCHEMBL29661840 0.90 ALDH1A1 (0.49) ALDH1A1MEN1MAPTKMT2AMITF
SCHEMBL22288258 0.90 ALDH1A1 (0.49) ALDH1A1MEN1MAPTKMT2AMITF
Benzene SCHEMBL28075690 0.88 ALDH1A1 (0.53) ALDH1A1MEN1MAPTKMT2AMITF
SCHEMBL1167375 0.88 ALDH1A1 (0.53) ALDH1A1MEN1MAPTKMT2AMITF
SCHEMBL2701544 0.88 ALDH1A1 (0.53) ALDH1A1MEN1MAPTKMT2AMITF
SCHEMBL5058743 0.88 ALDH1A1 (0.47) ALDH1A1MEN1MAPTKMT2AMITF
SCHEMBL5058738 0.88 ALDH1A1 (0.47) ALDH1A1MEN1MAPTKMT2AMITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10583972-B2 Polymer with blue light absorbing units chemically bonded to a polyermic backbone of the polymer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-03-10 US claimed