SCHEMBL22288258

SCHEMBL22288258

C(=C/c1cccc2cc3ccccc3cc12)\c1cccc2cc3ccccc3cc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
MEN1 O00255 2/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.49
CYP1A2 P05177 2/20 0.49
MITF O75030 1/20 0.49
CYP2C9 P11712 1/20 0.49
PKM P14618 1/20 0.49
MAPK1 P28482 1/20 0.49
RAB9A P51151 1/20 0.49
CCR6 P51684 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 2/20 0.44
CHAT P28329 5/20 0.43
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29661840 1.00 ALDH1A1 (0.49) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL5058743 0.98 ALDH1A1 (0.47) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL5058738 0.98 ALDH1A1 (0.47) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL29436024 0.90 RELA (0.52) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL21786017 0.90 ALDH1A1 (0.50) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL9000377 0.90 ALDH1A1 (0.43) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL51050 0.90 RELA (0.52) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL51049 0.90 RELA (0.52) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL30010383 0.90 RELA (0.52) ALDH1A1MEN1MAPTKMT2ACYP1A2
SCHEMBL5478882 0.88 RELA (0.50) ALDH1A1MEN1MAPTKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020155595-A1 AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR 清华大学 2020-08-06 WO disclosed